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HMG protocol on TRT?
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Old 02-08-2010, 06:57 PM
tat2ed tat2ed is offline
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HMG protocol on TRT?

What is the dosing schedule for HMG while on TRT?

Im only 27 and will be going on TRT in the next month. Im planning on having children in the future and want to remain fertile. From my research it seems like using HCG would not help with fertility issues since its like LH, which only stimulates the leydig cells to produce Test.

HMG is like FSH which stimulates the Sertoli cells which induce sperm production.

Could I run HMG alone or would it need to be ran w/ HCG?
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Old 02-08-2010, 08:09 PM
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Originally Posted by tat2ed View Post
What is the dosing schedule for HMG while on TRT?

Im only 27 and will be going on TRT in the next month. Im planning on having children in the future and want to remain fertile. From my research it seems like using HCG would not help with fertility issues since its like LH, which only stimulates the leydig cells to produce Test.

HMG is like FSH which stimulates the Sertoli cells which induce sperm production.

Could I run HMG alone or would it need to be ran w/ HCG?
Let me get some terms straight, first. Are you hypogonadal, requiring TRT? or are you saying you're about to start your first cycle and are calling it TRT?
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Old 02-08-2010, 09:20 PM
tat2ed tat2ed is offline
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Yes, I believe I'm hypogonadal. My last lab showed total Test at 195, but my LH and FSH are in range and my semen analysis came back with good potency and strong swimmers. This was back in the beginning of January.

I will post my most recent results when I get them tomorrow.

My Endo is very suspicious of AAS use and hasn't been very helpful thus far. I take it as a compliment since I have only done (2) six week cycles of Turinabol and that was over 2 years ago.

So far this has been a 6 month long process of Dr. visits, tests, wait and then more tests. F*CK HMO's, I dont know how much longer I can wait before I take matters into my own hands and start self medicating.
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Old 02-08-2010, 11:47 PM
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Originally Posted by tat2ed View Post
Yes, I believe I'm hypogonadal. My last lab showed total Test at 195, but my LH and FSH are in range and my semen analysis came back with good potency and strong swimmers. This was back in the beginning of January.

I will post my most recent results when I get them tomorrow.

My Endo is very suspicious of AAS use and hasn't been very helpful thus far. I take it as a compliment since I have only done (2) six week cycles of Turinabol and that was over 2 years ago.

So far this has been a 6 month long process of Dr. visits, tests, wait and then more tests. F*CK HMO's, I dont know how much longer I can wait before I take matters into my own hands and start self medicating.
Then I will shoot it to you straight: you ARE hypogonadal and neither HCG nor HMG will do any good. If the Leydig cells are dead, no amount of LH will cause them to produce testosterone. By your own acknowledgement, your blood work shows FSH and LH in normal ranges, yet your test is down. That means the Leydigs are the issue. You don't need PCT of any sort. You need HRT, period....forever on for the rest of your life. If you're going to cycle for growth, when you come off, just cruise on your HRT dose. That's what I do....
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Old 02-08-2010, 11:54 PM
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Originally Posted by Ironworker View Post
Then I will shoot it to you straight: you ARE hypogonadal and neither HCG nor HMG will do any good. If the Leydig cells are dead, no amount of LH will cause them to produce testosterone. By your own acknowledgement, your blood work shows FSH and LH in normal ranges, yet your test is down. That means the Leydigs are the issue. You don't need PCT of any sort. You need HRT, period....forever on for the rest of your life. If you're going to cycle for growth, when you come off, just cruise on your HRT dose. That's what I do....

Completely agree with IW. Listen to this brother, he knows his shit.
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Old 02-09-2010, 05:49 AM
tat2ed tat2ed is offline
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Thanks for giving it to me straight IW. I truly appreciate your no nonsense advice.

My thought was if my leydig cells are dead that my LH would be sky high trying to get them to react. I dont have the #'s, but my LH was on the low end of normal.

If the Leydigs are dead, I see why HCG would be pointless. How ever I am currently Fertile, which would mean my Sertoli cells are still functioning normally. At this point my main concerne is to stay fertile while on TRT.

What are your thoughts on the relationship between the Leydig and Sertoli cells. Could the the Leydigs be dead with the Sertoli cells still funtioning properly.

My Endo did say my testes were on the small side. I will post my latest lab as soon as I get the results.

Thanks
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Old 02-09-2010, 03:39 PM
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Originally Posted by tat2ed View Post
Thanks for giving it to me straight IW. I truly appreciate your no nonsense advice.

My thought was if my leydig cells are dead that my LH would be sky high trying to get them to react. I dont have the #'s, but my LH was on the low end of normal.

If the Leydigs are dead, I see why HCG would be pointless. How ever I am currently Fertile, which would mean my Sertoli cells are still functioning normally. At this point my main concerne is to stay fertile while on TRT.

What are your thoughts on the relationship between the Leydig and Sertoli cells. Could the the Leydigs be dead with the Sertoli cells still funtioning properly.

My Endo did say my testes were on the small side. I will post my latest lab as soon as I get the results.

Thanks
What matters is your sperm count, not your ball size (is your endo a woman...LOL!). If the HPTA is shut down, then FSH is low or shut down, which is the hormone that stimulates Sertoli cells to support sperm growth. In that case, Nolvadex (Tamoxifen) is the drug you want for the kckstart - see my thread in the PCT section labeled "Why the hell am I...." Start your PCT 10 days after your last long ester pinning and run for 3-4 weeks....all Tamoxifen.

Yes, a negative testosterone feedback to the HPTA would increase LH output, except in one case....and that's elevated estradiol. If your estrogen is high, your LH and FSH production would be muted. I'm suggesting in the above answer that estrogen might be your problem.

Trust your endo as far as diagnosis is concerned. But you might know more than her/him regarding a solution, so talk openly with them about what you've learned in your research.
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Old 02-09-2010, 05:00 PM
tat2ed tat2ed is offline
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In that case, Nolvadex (Tamoxifen) is the drug you want for the kckstart - see my thread in the PCT section labeled "Why the hell am I...." Start your PCT 10 days after your last long ester pinning and run for 3-4 weeks....all Tamoxifen.
This protocol may be difficult since Im planning on staying on TRT for life LOL.

What do you recommend I do to maintain fertility while ON TRT?
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Old 02-09-2010, 05:55 PM
tat2ed tat2ed is offline
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Latest lab results. I asked my Endo to check E2 but he said that wasn't important. When I tried to talk to him about what I thought I needed he said " Ya thats the problem with the internet everyone think they are an endocrinologist."

TT: 380 (250 - 1100)
FT: 84.4
LH: 2.8 (1.5 - 9.3)
FSH: 2.4 (1.6-8.0)
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Old 02-09-2010, 07:22 PM
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Regardless of what he thinks, he works for U, tell him what U want and see to it he does just that. If not, find one that will, they are out there, just have to find em, when U do, U want have to hear that type shit!! Shit pisses me off like no other!!
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Last edited by Biggin; 02-09-2010 at 07:22 PM.. Reason: ??
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