By Laura Dolson

Protein: How Much Do You Need?

What is protein? How much protein do we need? Is it possible to eat too much protein? These are important questions for people following a low carb way of eating, who usually are replacing part of their carbohydrate intake with protein.

read more>>

By Dan Wetzel

Lesnar’s rocky road takes another turn

Last month Brock Lesnar sat in a small-town, fast food restaurant, surrounded by blue-collar townies, munching on a five-dollar foot long. He was the reigning Ultimate Fighting Championship heavyweight title holder, yet unlike his old days as a profession

read more>>

By Bryan Smith

Exotic juice health claims are pure pulp fiction

They arrive early and join a line that stretches out like a Sunday morning communion queue: flip-flopped tourists in madras-print vestments, joggers ashine from their early-morning canters, locals burning off the fog of a few too many.

read more>>

femera

Description: Letrozole (INN, trade name Femara®) is an oral non-steroidal aromatase inhibitor that has been introduced for the adjuvant treatment of hormonally-responsive breast cancer.

Estrogens are produced by the conversion of androgens through the activity of the aromatase enzyme. Letrozole blocks production of estrogens in this way by competitive, reversible binding to the heme of its cytochrome P450 unit. The action is specific, and letrozole does not reduce production of mineralo- or corticosteroids. In contrast, the antiestrogenic action of tamoxifen, the major medical therapy prior to the arrival of aromatase inhibitors, is due to its interfering with the estrogen receptor, rather than inhibiting estrogen production.

Chemical name: Letrozole

Chem. Abstr. Name: 4-[(4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl] benzonitrile

Molecular Weight: 285.303 g/mol

Molecular Structure: C₁₇H₁₁N₅

CAS Number: 112809-51-5

Merck Index Number: n/a

Metabolism: n/a

Excretion: n/a

Elimination Half Life: 2 days